Melissa A Laramore Selected Research

Sepharose (Agarose)

2/2018	Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer: Evaluation of a biological-systems approach to cancer therapy (U.S. FDA IND-BB 10091; NCT 02046174, NCT 01053013).
8/2016	Retention of gene expression in porcine islets after agarose encapsulation and long-term culture.
1/2014	No evidence of viral transmission following long-term implantation of agarose encapsulated porcine islets in diabetic dogs.
1/2014	Enhancement of in vitro and in vivo function of agarose-encapsulated porcine islets by changes in the islet microenvironment.
12/2013	Treatment of agarose-agarose RENCA macrobeads with docetaxel selects for OCT4(+) cells with tumor-initiating capability.
2/2011	Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties.
2/2011	Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth.

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Melissa A Laramore Research Topics

Disease

4	Neoplasms (Cancer) 02/2018 - 02/2011
3	Renal Cell Carcinoma (Grawitz Tumor) 02/2018 - 02/2011
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2016 - 01/2014
2	Diabetes Mellitus 01/2014 - 01/2014
1	Inflammation (Inflammations) 02/2018
1	Colorectal Neoplasms (Colorectal Cancer) 02/2018
1	Carcinoma (Carcinomatosis) 02/2011
1	Weight Gain 01/2007

Drug/Important Bio-Agent (IBA)

7	Sepharose (Agarose)IBA 02/2018 - 02/2011
3	Insulin (Novolin)FDA Link 11/2016 - 01/2007
1	Carcinoembryonic AntigenIBA 02/2018
1	Lactate Dehydrogenase 5IBA 02/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 02/2018
1	Biological ProductsIBA 02/2018
1	Tumor Biomarkers (Tumor Markers)IBA 02/2018
1	AntigensIBA 02/2018
1	Pravastatin (Pravachol)FDA LinkGeneric 01/2014
1	SolutionsIBA 01/2014
1	Streptozocin (Streptozotocin)FDA Link 01/2014
1	Docetaxel (Taxotere)FDA Link 12/2013
1	Proteins (Proteins, Gene)FDA Link 02/2011
1	Bromodeoxyuridine (BrdU)IBA 02/2011
1	Conditioned Culture MediaIBA 02/2011
1	Caspase 3 (Caspase-3)IBA 02/2011

Therapy/Procedure

3	Therapeutics 02/2018 - 01/2007
3	Transplantation 01/2014 - 12/2013
1	Heterologous Transplantation (Xenotransplantation) 01/2014
1	Drug Therapy (Chemotherapy) 12/2013